Cell Lines

hERG Safety Assessment

Screening Service

Assay Development

flyion is offering a variety of ion channel targets, expressed in a CHO cell line. The focus of this service was to provide stable cell lines with an inducible target. Thus the problem of overexpression or cell toxicity by ion flux can be overcome. Every target has been thouroughly characterized and validated by electrophysiological and pharmacological means.

The following cell lines are available:

Targets in CHO cells

  • hERG
  • Kir2.1
  • KCNQ1
  • Slo1_BK
  • Nav1.1

In addition we have experience with the following targets: TRPM8, TRPM7, TRPV1, T-type Ca2+ channel, hNav1.3, mitochondrial Vrac, LTK-Kv1.5, and nACh-R. Corresponding expression systems in CHO cells can be provided quickly

Located in Tübingen, Germany, flyion GmbH provides fast, confidential, and customer tailored cell lines.

For more information please use the following link: Cell Lines or contact us for pricing.

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