Patch clamp screening economy critically depends on the costs for consumables, since gigaseal recording chambers can not be reused.

Therefore, Flyscreen^® utilizes competitively priced glass
tips that provide a proven substrate for high quality gigaseals. Furthermore, the Flyscreen^® robot uses individual recording tips. That means no waste of recording positions at maximal throughput speed. In contrast, a fixed array of recording chips wastes time and money, since
chips that lack a good recording have to wait for their neighbors to complete the screen. If anything goes wrong with cell culture, costly multiwell chips are wasted before the problem can be fixed. Unlike the chips, the Flyscreen^® robot exchanges individual recording tips independently. The user can choose from single recording mode to test cell culture conditions up to the full scale, asynchronous, parallel recording mode.